Home Fertlility Treatments Ovulation Induction



A frequently observed condition is infertility due to ovulation disorders. Many circumstances lead to this condition, such as obesity, increase in prolactin secretion and the Polycystic Ovarian Syndrome. Alterations in the GnRH secretion by the hypothalamus or FSH and LH by hypophysis may lead to anovulation . Those late hormones are directly responsible for recruiting, developing and maturing the ovulatory follicles inside of which the egg lays.

To correct the disorder many treatments may be employed to ovarian stimulation. The clomiphene citrate and FSH or FSH + LH-rich mixtures are the most frequently utilized resources.

Lately, FSH-rich mixtures obtained from menopaused-women urine are being replaced by genetically-engineered synthetic mixtures (Recombinat FSH an LH) that boasts higher purity and efficacy attaining better results in ovulation induction.

Ovulation induction is an individual process done particularly for each woman. The protocols, dosage and medicines to be prepared and applied are also personalized according to each woman profile. In some cases protocols are aimed at the production of 2, 3 eggs in one single cycle thus increasing pregnancy rates in a process called planned intercourse.

A crucial part in this process is monitoring the ovarian response to medication. Monitoring is aimed at three basic topics:

1 – Verify the protocol efficacy in the ovarian response through the production of the ovulatory follicle.

2- Detect hyperstimulation in the ovarian response through the production of various follicles thus preventing the risk of multiple gestations.

3- Determine precisely the best day to the administration of chorionic gonadotropin to induce the follicle final maturation, its rupture and, consequently, the best day for intercourse.

Monitoring is carried mainly through transvaginal ultrasound. Exams are performed in a row to determine follicle diameter and the endometrium thickness. Blood samples for hormonal assay may be necessary to evaluate the follicle quality.

Depending on the drugs used we will follow the follicle growth to a certain diameter when ovulation is thus induced with administration of hCG. After 36 hours the ovulation process begins through the liberation of the eggs which are captured by the fallopian tubes. And this is the period we advice the patient to perform intercourse.

With the new drugs available success in ovulation induction highly increases opening new hopes to poor responders patients and older woman.




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